• Changzhou Yabang-QH Pharmachem Co., Ltd.
    婷婷五月中文字幕在线-亚洲视频在线看-先の欲求不満な人妻在线-最新免费高清无码专区
      API For Human Use
      API For Veterinary Use
      Pharmaceutical Intermediates
         
       
     
    Luxalbendazole
    Synonyms:

    * Luxabendazolum [Latin]
    * 2-Benzimidazolecarbamate, 5-hydroxy-, p-fluorobenzenesulfoonate
    * Methyl 5-hydroxy-2-benzimidazolecarbamate, p-fluorobenzenesulfonate (ester)
    * Luxabendazole [BAN:INN] * Luxabendazol [Spanish]
    * CCRIS 7645 * HOE 216V

    Chemical Name:
    methyl N-[5-(4-fluorophenyl)sulfonyloxy-3H-benzoimidazol-2-yl]carbamate
    Molecular Formula:

    365.337

    Molecular Weight :
    365.337
    CAS No. :
    90509-02-7
    Chemical Structure:
    Specification:
    In-house spec
    Pharmacodynamic
    Properties
    :

    Luxabendazole(LBZ) is a new benzimidazole carbamate chemotherapeutic agent. It binds to the structural protein tubulin, thereby preventing its polymerization to microtubules which provide the transport system for the absorbing cells. The consequence of blocking this transport activity is incomplete absorption and digestion of nutrient particles and cellular autolysis through activation of lysosomal enzymes.
    Luxabendazole(LBZ) has proved to be effective against adult and immature stages of the major gastrointestinal nematodes, trematodes and cestodes.
    Based on the scientific study on the anthelmintic potential of luxabendazole (department of General Zoology and Parasitology, University of Veterinary Science, Budapest, Hungary), a single oral treatment at doses of 10.0 or 12.5 mg/kg body wt removed 97.6% of the adult Fasciola hepatica and 63.2%-83.8% of the Dicrocoelium dendriticum. Luxabendazole at 7.5, 10.0, and 12.5 mg/kg proved 100% effective in removing adult worms of the genera Haemonchus, Ostertagia, Trichostrongylus, Cooperia and Nematodirus as well as tissue-associated larval stages of gastrointestinal nematodes of the abomasal mucosa. The drug showed an intensity effect of 79.7%-87.6% against Strongyloides papillosus. Luxabendazole removed all Dictyocaulus filaria and reduced the fecal excretion of larvae of protostrongylid species (Protostrongylus rufescens, Neostrongylus linearis, Cystocaulus ocreatus, Muellerius capillaris) by 97.8%-99.6%.

    Storage:
    Keep container tightly closed in a cool, well-ventilated area.
    MSDS:
    Provide as per request after the order or contract is signed.
     
      [Disclaimer]
    (1) All rights reserved. Reproduction in whole or part expressly forbidden without written permission.
    (2) We make effort to ensure the information presented here is accurate, but does not purport to be all inclusive and shall be used only as a reference.
    (3) We make no warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes.
     
    Copyright(C)2013,Jiangsu Quality Horizons Pharmtech Co., Ltd. All Rights Reserved. Supported by ChemNet ChinaChemNet Toocle Copyright Notice